Found 309 results. Export: Tagged | XML
1995
de Lange, E.C., Hesselink, M.B., Danhof, M., de Boer, A.G., Breimer, D.D. , The use of intracerebral microdialysis to determine changes in blood-brain barrier transport characteristics, Pharm Res, vol. 12, no. 1, pp. 129-33.
Mathot, R.A., Cleton, A., Soudijn, W., AP, I.J., Danhof, M. , Pharmacokinetic modelling of the haemodynamic effects of the A2a adenosine receptor agonist CGS 21680C in conscious normotensive rats, Br J Pharmacol, vol. 114, no. 4, pp. 761-8.
de Lange, E.C., Danhof, M., Zurcher, C., de Boer, A.G., Breimer, D.D. , Repeated microdialysis perfusions: periprobe tissue reactions and BBB permeability, Brain Res, vol. 702, no. 1-2, pp. 261-5. DOI
de Lange, E.C., de Vries, J.D., Zurcher, C., Danhof, M., de Boer, A.G., Breimer, D.D. , The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain, Pharm Res, vol. 12, no. 12, pp. 1924-31.
Van der Wenden, E.M., Hartog-Witte, H.R., Roelen, H.C., von Frijtag Drabbe Kunzel, J.K., Pirovano, I.M., Mathot, R.A., Danhof, M., Van Aerschot, A., Lidaks, M.J., AP, I.J., , . et al., 8-substituted adenosine and theophylline-7-riboside analogues as potential partial agonists for the adenosine A1 receptor, Eur J Pharmacol, vol. 290, no. 3, pp. 189-99.
Appel, S., Mathot, R.A., Langemeijer, M.W., AP, I.J., Danhof, M. , Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline, Br J Pharmacol, vol. 115, no. 7, pp. 1253-9.
Mathot, R.A., Van den Aarsen, B.C., Soudijn, W., Breimer, D.D., Ijzerman, A.P., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of R- and S-N6-phenylisopropyladenosine in conscious normotensive rats, J Pharmacol Exp Ther, vol. 273, no. 1, pp. 405-14.
Hoyo-Vadillo, C., Mandema, J.W., Danhof, M. , Pharmacodynamic interaction between midazolam and a low dose of ethanol in vivo, Life Sci, vol. 57, no. 4, pp. 325-33. DOI
1994
Hoogerkamp, A., Vis, P.W., Danhof, M., Voskuyl, R.A. , Characterization of the pharmacodynamics of several antiepileptic drugs in a direct cortical stimulation model of anticonvulsant effect in the rat, J Pharmacol Exp Ther, vol. 269, no. 2, pp. 521-8.
Mathot, R.A., Van den Aarsen, B.C., von Frijtag Drabble Kunzel, J.K., Danhof, M., Ijzerman, A.P. , Assessment of the enantiomeric purity of R- and S-N6-phenylisopropyladenosine (PIA): implications for adenosine receptor subclassification, Naunyn Schmiedebergs Arch Pharmacol, vol. 350, no. 1, pp. 109-12.
Mathot, R.A., van Schaick, E.A., Langemeijer, M.W., Soudijn, W., Breimer, D.D., Ijzerman, A.P., Danhof, M. , Pharmacokinetic-pharmacodynamic relationship of the cardiovascular effects of adenosine A1 receptor agonist N6-cyclopentyladenosine in the rat, J Pharmacol Exp Ther, vol. 268, no. 2, pp. 616-24.
de Lange, E.C., Danhof, M., de Boer, A.G., Breimer, D.D. , Critical factors of intracerebral microdialysis as a technique to determine the pharmacokinetics of drugs in rat brain, Brain Res, vol. 666, no. 1, pp. 1-8.
AP, I.J., van der Wenden, E.M., von Frijtag Drabbe Kunzel, J.K., Mathot, R.A., Danhof, M., Borea, P.A., Varani, K. , Partial agonism of theophylline-7-riboside on adenosine receptors, Naunyn Schmiedebergs Arch Pharmacol, vol. 350, no. 6, pp. 638-45.
Irth, H., Cleton, A., Mathot, R.A., Danhof, M., AP, I.J., Tjaden, U.R., van der Greef, J. , Liquid chromatographic determination of the adenosine receptor agonist CGS 21680 in blood using on-line solid-phase extraction on a phenylboronic acid support and fluorescence detection, J Chromatogr B Biomed Appl, vol. 658, no. 1, pp. 207-12.
Vinks, A.A., Touw, D.J., Heijerman, H.G., Danhof, M., de Leede, G.P., Bakker, W. , Pharmacokinetics of ceftazidime in adult cystic fibrosis patients during continuous infusion and ambulatory treatment at home, Ther Drug Monit, vol. 16, no. 4, pp. 341-8.
1993
Stijnen, A.M., Hovinga, S., Langemeijer, M.W., Hoogerkamp, A., van Bezooijen, C.F., Danhof, M. , Increased sensitivity to the anticonvulsant effect of valproate in aging BN/BiRij rats, Pharm Res, vol. 10, no. 7, pp. 1046-51.
Danhof, M., Mandema, J.W., Hoogerkamp, A., Mathot, R.A. , Pharmacokinetic-pharmacodynamic modelling in pre-clinical investigations: principles and perspectives, Eur J Drug Metab Pharmacokinet, vol. 18, no. 1, pp. 41-7.
Van Bree, J.B., De Boer, A.G., Danhof, M., Breimer, D.D. , Drug transport across the blood-brain barrier. III. Mechanisms and methods to improve drug delivery to the central nervous system, Pharm World Sci, vol. 15, no. 1, pp. 2-9.
Van Steveninck, A.L., Mandema, J.W., Tuk, B., Van Dijk, J.G., Schoemaker, H.C., Danhof, M., Cohen, A.F. , A comparison of the concentration-effect relationships of midazolam for EEG-derived parameters and saccadic peak velocity, Br J Clin Pharmacol, vol. 36, no. 2, pp. 109-15.
de Lange, E.C., Danhof, M., de Boer, A.G., Breimer, D.D. , The use of intracerebral microdialysis to study blood-brain barrier transport in health, after modification and in disease, Adv Exp Med Biol, vol. 331, pp. 257-62.
1992
Hovinga, S., Stijnen, A.M., Langemeijer, M.W., Mandema, J.W., van Bezooijen, C.F., Danhof, M. , Pharmacokinetic-EEG effect relationship of midazolam in aging BN/BiRij rats, Br J Pharmacol, vol. 107, no. 1, pp. 171-7.
Stijnen, A.M., Postel-Westra, I, Langemeijer, M.W., Hoogerkamp, A., Voskuyl, R.A., van Bezooijen, C.F., Danhof, M. , Pharmacodynamics of the anticonvulsant effect of oxazepam in aging BN/BiRij rats, Br J Pharmacol, vol. 107, no. 1, pp. 165-70.
Van Bree, J.B., De Boer, A.G., Danhof, M., Breimer, D.D. , Drug transport across the blood--brain barrier. I. Anatomical and physiological aspects, Pharm Weekbl Sci, vol. 14, no. 5, pp. 305-10.
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