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2009
Ploeger, B.A., Smeets, J., Strougo, A., Drenth, H.J., Ruigt, G., Houwing, N., Danhof, M. , Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex, Anesthesiology, vol. 110, no. 1, pp. 95-105. DOI
2008
Santen, G., Danhof, M., Della Pasqua, O. , Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model, J Psychiatr Res, vol. 42, no. 14, pp. 1189-97. DOI
Santen, G., Gomeni, R., Danhof, M., Della Pasqua, O. , Sensitivity of the individual items of the Hamilton depression rating scale to response and its consequences for the assessment of efficacy, J Psychiatr Res, vol. 42, no. 12, pp. 1000-9. DOI
Peeters, M.Y., Bras, L.J., DeJongh, J., Wesselink, R.M., Aarts, L.P., Danhof, M., Knibbe, C.A. , Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients, Clin Pharmacol Ther, vol. 83, no. 3, pp. 443-51. DOI
Peeters, M.Y., Aarts, L.P., Boom, F.A., Bras, L.J., Tibboel, D., Danhof, M., Knibbe, C.A. , Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients, Eur J Clin Pharmacol, vol. 64, no. 3, pp. 329-34. DOI
Maas, H.J., Snelder, N., Danhof, M., Della Pasqua, O. , Prediction of attack frequency in migraine treatment, Cephalalgia, vol. 28, no. 8, pp. 847-55. DOI
Post, T.M., Freijer, J. I, Ploeger, B.A., Danhof, M. , Extensions to the visual predictive check to facilitate model performance evaluation, J Pharmacokinet Pharmacodyn, vol. 35, no. 2, pp. 185-202. DOI
Danhof, M., de Lange, E.C., Della Pasqua, O.E., Ploeger, B.A., Voskuyl, R.A. , Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research, Trends Pharmacol Sci, vol. 29, no. 4, pp. 186-91. DOI
Maas, H.J., Spruit, M.A., Danhof, M., Della Pasqua, O.E. , Relevance of absorption rate and lag time to the onset of action in migraine, Clin Pharmacokinet, vol. 47, no. 2, pp. 139-46. DOI
2007
Anisimov, V.V., Maas, H.J., Danhof, M., Della Pasqua, O. , Analysis of responses in migraine modelling using hidden Markov models, Stat Med, vol. 26, no. 22, pp. 4163-78. DOI
Muller, A.E., DeJongh, J., Bult, Y., Goessens, W.H., Mouton, J.W., Danhof, M., van den Anker, J.N. , Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks, Antimicrob Agents Chemother, vol. 51, no. 10, pp. 3720-5. DOI
Zuideveld, K.P., Van der Graaf, P.H., Peletier, L.A., Danhof, M. , Allometric scaling of pharmacodynamic responses: application to 5-Ht1A receptor mediated responses from rat to man, Pharm Res, vol. 24, no. 11, pp. 2031-9. DOI
Freijer, J. I, Post, T.M., Ploeger, B.A., DeJongh, J., Danhof, M. , Application of the convection-dispersion equation to modelling oral drug absorption, Bull Math Biol, vol. 69, no. 1, pp. 181-95. DOI
Yassen, A., Olofsen, E., Romberg, R., Sarton, E., Teppema, L., Danhof, M., Dahan, A. , Mechanism-based PK/PD modeling of the respiratory depressant effect of buprenorphine and fentanyl in healthy volunteers, Clin Pharmacol Ther, vol. 81, no. 1, pp. 50-8. DOI
Rolan, P., Danhof, M., Stanski, D., Peck, C. , Current issues relating to drug safety especially with regard to the use of biomarkers: a meeting report and progress update, Eur J Pharm Sci, vol. 30, no. 2, pp. 107-12. DOI
Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine, Clin Pharmacokinet, vol. 46, no. 5, pp. 433-47. DOI
Danhof, M., de Jongh, J., De Lange, E.C., Della Pasqua, O., Ploeger, B.A., Voskuyl, R.A. , Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis, Annu Rev Pharmacol Toxicol, vol. 47, pp. 357-400. DOI
Yassen, A., Olofsen, E., van Dorp, E., Sarton, E., Teppema, L., Danhof, M., Dahan, A. , Mechanism-based pharmacokinetic-pharmacodynamic modelling of the reversal of buprenorphine-induced respiratory depression by naloxone : a study in healthy volunteers, Clin Pharmacokinet, vol. 46, no. 11, pp. 965-80. DOI
2006
Maas, H.J., Danhof, M., Della Pasqua, O. , A model-based approach to treatment comparison in acute migraine, Br J Clin Pharmacol, vol. 62, no. 5, pp. 591-600. DOI
Dahan, A., Yassen, A., Romberg, R., Sarton, E., Teppema, L., Olofsen, E., Danhof, M. , Buprenorphine induces ceiling in respiratory depression but not in analgesia, Br J Anaesth, vol. 96, no. 5, pp. 627-32. DOI
Peeters, M.Y., Prins, S.A., Knibbe, C.A., DeJongh, J., van Schaik, R.H., van Dijk, M., van der Heiden, I.P., Tibboel, D., Danhof, M. , Propofol pharmacokinetics and pharmacodynamics for depth of sedation in nonventilated infants after major craniofacial surgery, Anesthesiology, vol. 104, no. 3, pp. 466-74. DOI
Swart, E.L., Zuideveld, K.P., de Jongh, J., Danhof, M., Thijs, L.G., van Strack Schijndel, R.M. , Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients, Eur J Clin Pharmacol, vol. 62, no. 3, pp. 185-94. DOI
Huntjens, D.R., Spalding, D.J., Danhof, M., Della Pasqua, O.E. , Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers, Br J Pharmacol, vol. 148, no. 4, pp. 396-404. DOI
Yassen, A., Olofsen, E., Romberg, R., Sarton, E., Danhof, M., Dahan, A. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine in healthy volunteers, Anesthesiology, vol. 104, no. 6, pp. 1232-42. DOI
van Dorp, E., Yassen, A., Sarton, E., Romberg, R., Olofsen, E., Teppema, L., Danhof, M., Dahan, A. , Naloxone reversal of buprenorphine-induced respiratory depression, Anesthesiology, vol. 105, no. 1, pp. 51-7. DOI
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