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2009
Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., de Jong, H.W., Dijkstra, J., van der Weerd, L., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Changes in GABAA receptor properties in amygdala kindled animals: in vivo studies using [11C]flumazenil and positron emission tomography, Epilepsia, vol. 50, no. 1, pp. 88-98. DOI
Ploeger, B.A., Smeets, J., Strougo, A., Drenth, H.J., Ruigt, G., Houwing, N., Danhof, M. , Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex, Anesthesiology, vol. 110, no. 1, pp. 95-105. DOI
2008
Santen, G., Danhof, M., Della Pasqua, O. , Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model, J Psychiatr Res, vol. 42, no. 14, pp. 1189-97. DOI
Santen, G., Gomeni, R., Danhof, M., Della Pasqua, O. , Sensitivity of the individual items of the Hamilton depression rating scale to response and its consequences for the assessment of efficacy, J Psychiatr Res, vol. 42, no. 12, pp. 1000-9. DOI
Ravenstijn, P.G., Merlini, M., Hameetman, M., Murray, T.K., Ward, M.A., Lewis, H., Ball, G., Mottart, C., de Ville Goyet, C., Lemarchand, T., van Belle, K., O'Neill, M.J., Danhof, M., de Lange, E.C. , The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments, J Pharmacol Toxicol Methods, vol. 57, no. 2, pp. 114-30. DOI
Peeters, M.Y., Bras, L.J., DeJongh, J., Wesselink, R.M., Aarts, L.P., Danhof, M., Knibbe, C.A. , Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients, Clin Pharmacol Ther, vol. 83, no. 3, pp. 443-51. DOI
Groenendaal, D., Freijer, J., Rosier, A., de Mik, D., Nicholls, G., Hersey, A., Ayrton, A.D., Danhof, M., de Lange, E.C. , Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci, vol. 34, no. 2-3, pp. 149-63. DOI
Muller, A.E., DeJongh, J., Oostvogel, P.M., Voskuyl, R.A., Dorr, P.J., Danhof, M., Mouton, J.W. , Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6. DOI
Clinckers, R., Smolders, I, Michotte, Y., Ebinger, G., Danhof, M., Voskuyl, R.A., Della Pasqua, O. , Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain, Br J Pharmacol, vol. 155, no. 7, pp. 1127-38. DOI
Muller, A.E., Dorr, P.J., Mouton, J.W., De Jongh, J., Oostvogel, P.M., Steegers, E.A., Voskuyl, R.A., Danhof, M. , The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women, Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74. DOI
Maas, H.J., Snelder, N., Danhof, M., Della Pasqua, O. , Prediction of attack frequency in migraine treatment, Cephalalgia, vol. 28, no. 8, pp. 847-55. DOI
Post, T.M., Freijer, J. I, Ploeger, B.A., Danhof, M. , Extensions to the visual predictive check to facilitate model performance evaluation, J Pharmacokinet Pharmacodyn, vol. 35, no. 2, pp. 185-202. DOI
Maas, H.J., Spruit, M.A., Danhof, M., Della Pasqua, O.E. , Relevance of absorption rate and lag time to the onset of action in migraine, Clin Pharmacokinet, vol. 47, no. 2, pp. 139-46. DOI
2007
Anisimov, V.V., Maas, H.J., Danhof, M., Della Pasqua, O. , Analysis of responses in migraine modelling using hidden Markov models, Stat Med, vol. 26, no. 22, pp. 4163-78. DOI
Zuideveld, K.P., Van der Graaf, P.H., Peletier, L.A., Danhof, M. , Allometric scaling of pharmacodynamic responses: application to 5-Ht1A receptor mediated responses from rat to man, Pharm Res, vol. 24, no. 11, pp. 2031-9. DOI
Geldof, M., Freijer, J., van Beijsterveldt, L., Vermote, P.C., Megens, A.A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine on p-chloroamphetamine-induced behavior, Eur J Pharm Sci, vol. 32, no. 3, pp. 200-8. DOI
Yassen, A., Kan, J., Olofsen, E., Suidgeest, E., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of norbuprenorphine in rats, J Pharmacol Exp Ther, vol. 321, no. 2, pp. 598-607. DOI
Jonker, D.M., Voskuyl, R.A., Danhof, M. , Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments?, Epilepsia, vol. 48, no. 3, pp. 412-34. DOI
van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint, Br J Pharmacol, vol. 151, no. 3, pp. 356-66. DOI
Liefaard, L.C., Gunput, R.A., Danhof, M., Voskuyl, R.A. , Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy, Epilepsia, vol. 48, no. 7, pp. 1378-87. DOI
Groenendaal, D., Freijer, J., de Mik, D., Bouw, M.R., Danhof, M., de Lange, E.C. , Influence of biophase distribution and P-glycoprotein interaction on pharmacokinetic-pharmacodynamic modelling of the effects of morphine on the EEG, Br J Pharmacol, vol. 151, no. 5, pp. 713-20. DOI
Groenendaal, D., Freijer, J., de Mik, D., Bouw, M.R., Danhof, M., de Lange, E.C. , Population pharmacokinetic modelling of non-linear brain distribution of morphine: influence of active saturable influx and P-glycoprotein mediated efflux, Br J Pharmacol, vol. 151, no. 5, pp. 701-12. DOI
Geldof, M., Freijer, J., van Beijsterveldt, L., Timmerman, P., Ahnaou, A., Drinkenburg, W.H., Danhof, M. , Population pharmacokinetic model of fluvoxamine in rats: utility for application in animal behavioral studies, Eur J Pharm Sci, vol. 30, no. 1, pp. 45-55. DOI
Rolan, P., Danhof, M., Stanski, D., Peck, C. , Current issues relating to drug safety especially with regard to the use of biomarkers: a meeting report and progress update, Eur J Pharm Sci, vol. 30, no. 2, pp. 107-12. DOI
Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine, Clin Pharmacokinet, vol. 46, no. 5, pp. 433-47. DOI
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