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2008
van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther, vol. 324, no. 3, pp. 1234-42. DOI
Huntjens, D.R., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D.J., Danhof, M., Della Pasqua, O. , Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats, Br J Pharmacol, vol. 153, no. 5, pp. 1072-84. DOI
Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78. DOI
Muller, A.E., DeJongh, J., Oostvogel, P.M., Voskuyl, R.A., Dorr, P.J., Danhof, M., Mouton, J.W. , Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6. DOI
Clinckers, R., Smolders, I, Michotte, Y., Ebinger, G., Danhof, M., Voskuyl, R.A., Della Pasqua, O. , Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain, Br J Pharmacol, vol. 155, no. 7, pp. 1127-38. DOI
Muller, A.E., Dorr, P.J., Mouton, J.W., De Jongh, J., Oostvogel, P.M., Steegers, E.A., Voskuyl, R.A., Danhof, M. , The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women, Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74. DOI
Maas, H.J., Snelder, N., Danhof, M., Della Pasqua, O. , Prediction of attack frequency in migraine treatment, Cephalalgia, vol. 28, no. 8, pp. 847-55. DOI
Geldof, M., Freijer, J., van Beijsterveldt, L., Danhof, M. , Pharmacokinetic modeling of non-linear brain distribution of fluvoxamine in the rat, Pharm Res, vol. 25, no. 4, pp. 792-804. DOI
2007
Muller, A.E., DeJongh, J., Bult, Y., Goessens, W.H., Mouton, J.W., Danhof, M., van den Anker, J.N. , Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks, Antimicrob Agents Chemother, vol. 51, no. 10, pp. 3720-5. DOI
Geldof, M., Freijer, J., van Beijsterveldt, L., Vermote, P.C., Megens, A.A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effect of fluvoxamine on p-chloroamphetamine-induced behavior, Eur J Pharm Sci, vol. 32, no. 3, pp. 200-8. DOI
Yassen, A., Kan, J., Olofsen, E., Suidgeest, E., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of norbuprenorphine in rats, J Pharmacol Exp Ther, vol. 321, no. 2, pp. 598-607. DOI
van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Pharmacokinetic-pharmacodynamic modelling of S(-)-atenolol in rats: reduction of isoprenaline-induced tachycardia as a continuous pharmacodynamic endpoint, Br J Pharmacol, vol. 151, no. 3, pp. 356-66. DOI
Liefaard, L.C., Gunput, R.A., Danhof, M., Voskuyl, R.A. , Decreased Efficacy of GABAA-receptor modulation by midazolam in the kainate model of temporal lobe epilepsy, Epilepsia, vol. 48, no. 7, pp. 1378-87. DOI
Freijer, J. I, Post, T.M., Ploeger, B.A., DeJongh, J., Danhof, M. , Application of the convection-dispersion equation to modelling oral drug absorption, Bull Math Biol, vol. 69, no. 1, pp. 181-95. DOI
Rolan, P., Danhof, M., Stanski, D., Peck, C. , Current issues relating to drug safety especially with regard to the use of biomarkers: a meeting report and progress update, Eur J Pharm Sci, vol. 30, no. 2, pp. 107-12. DOI
Yassen, A., Olofsen, E., van Dorp, E., Sarton, E., Teppema, L., Danhof, M., Dahan, A. , Mechanism-based pharmacokinetic-pharmacodynamic modelling of the reversal of buprenorphine-induced respiratory depression by naloxone : a study in healthy volunteers, Clin Pharmacokinet, vol. 46, no. 11, pp. 965-80. DOI
2006
Maas, H.J., Danhof, M., Della Pasqua, O. , A model-based approach to treatment comparison in acute migraine, Br J Clin Pharmacol, vol. 62, no. 5, pp. 591-600. DOI
Dahan, A., Yassen, A., Romberg, R., Sarton, E., Teppema, L., Olofsen, E., Danhof, M. , Buprenorphine induces ceiling in respiratory depression but not in analgesia, Br J Anaesth, vol. 96, no. 5, pp. 627-32. DOI
Swart, E.L., Zuideveld, K.P., de Jongh, J., Danhof, M., Thijs, L.G., van Strack Schijndel, R.M. , Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients, Eur J Clin Pharmacol, vol. 62, no. 3, pp. 185-94. DOI
van Dorp, E., Yassen, A., Sarton, E., Romberg, R., Olofsen, E., Teppema, L., Danhof, M., Dahan, A. , Naloxone reversal of buprenorphine-induced respiratory depression, Anesthesiology, vol. 105, no. 1, pp. 51-7. DOI
Nugroho, A.K., Romeijn, S.G., Zwier, R., de Vries, J.B., Dijkstra, D., Wikstrom, H., Della-Pasqua, O., Danhof, M., Bouwstra, J.A. , Pharmacokinetics and pharmacodynamics analysis of transdermal iontophoresis of 5-OH-DPAT in rats: in vitro-in vivo correlation, J Pharm Sci, vol. 95, no. 7, pp. 1570-85. DOI
Peeters, M.Y., Prins, S.A., Knibbe, C.A., Dejongh, J., Mathot, R.A., Warris, C., van Schaik, R.H., Tibboel, D., Danhof, M. , Pharmacokinetics and pharmacodynamics of midazolam and metabolites in nonventilated infants after craniofacial surgery, Anesthesiology, vol. 105, no. 6, pp. 1135-46. DOI
Maas, H.J., Danhof, M., Della Pasqua, O.E. , Prediction of headache response in migraine treatment, Cephalalgia, vol. 26, no. 4, pp. 416-22. DOI
2005
Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., Boellaard, R., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo by positron emission tomography, Mol Imaging Biol, vol. 7, no. 6, pp. 411-21. DOI
Schaddelee, M.P., Collins, S.D., DeJongh, J., de Boer, A.G., Ijzerman, A.P., Danhof, M. , Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain, Eur J Pharmacol, vol. 514, no. 2-3, pp. 131-40. DOI
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