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2005
Li, G.L., de Vries, J.J., van Steeg, T.J., van den Bussche, H., Maas, H.J., Reeuwijk, H.J., Danhof, M., Bouwstra, J.A., van Laar, T. , Transdermal iontophoretic delivery of apomorphine in patients improved by surfactant formulation pretreatment, J Control Release, vol. 101, no. 1-3, pp. 199-208. DOI
1999
van Laar, T., Van der Geest, R., Danhof, M. , Future delivery systems for apomorphine in patients with Parkinson's disease, Adv Neurol, vol. 80, pp. 535-44.
1998
Bodde, H.E., Van Laar, T., Van der Geest, R., Danhof, M. , An integrated pharmacokinetic-pharmacodynamic approach to optimization of R-apomorphine delivery in Parkinson's disease, Adv Drug Deliv Rev, vol. 33, no. 3, pp. 253-263. DOI
van der Geest, R., van Laar, T., Kruger, P.P., Gubbens-Stibbe, J.M., Bodde, H.E., Roos, R.A., Danhof, M. , Pharmacokinetics, enantiomer interconversion, and metabolism of R-apomorphine in patients with idiopathic Parkinson's disease, Clin Neuropharmacol, vol. 21, no. 3, pp. 159-68.
van Laar, T., van der Geest, R., Danhof, M., Bodde, H.E., Goossens, P.H., Roos, R.A. , Stepwise intravenous infusion of apomorphine to determine the therapeutic window in patients with Parkinson's disease, Clin Neuropharmacol, vol. 21, no. 3, pp. 152-8.
1997
van der Geest, R., Kruger, P., Gubbens-Stibbe, J.M., van Laar, T., Bodde, H.E., Danhof, M. , Assay of R-apomorphine, S-apomorphine, apocodeine, isoapocodeine and their glucuronide and sulfate conjugates in plasma and urine of patients with Parkinson's disease, J Chromatogr B Biomed Sci Appl, vol. 702, no. 1-2, pp. 131-41.
van der Geest, R., van Laar, T., Gubbens-Stibbe, J.M., Bodde, H.E., Danhof, M. , Iontophoretic delivery of apomorphine. II: An in vivo study in patients with Parkinson's disease, Pharm Res, vol. 14, no. 12, pp. 1804-10.
1996
van Laar, T., Neef, C., Danhof, M., Roon, K. I, Roos, R.A. , A new sublingual formulation of apomorphine in the treatment of patients with Parkinson's disease, Mov Disord, vol. 11, no. 6, pp. 633-8. DOI
1995
van Laar, T., Jansen, E.N., Neef, C., Danhof, M., Roos, R.A. , Pharmacokinetics and clinical efficacy of rectal apomorphine in patients with Parkinson's disease: a study of five different suppositories, Mov Disord, vol. 10, no. 4, pp. 433-9. DOI