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- 2007
Allometric scaling of pharmacodynamic responses: application to 5-Ht1A receptor mediated responses from rat to man,
Pharm Res, vol. 24, no. 11, pp. 2031-9. DOI
- 2006
Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients,
Eur J Clin Pharmacol, vol. 62, no. 3, pp. 185-94. DOI
- 2005
Allometric relationships between the pharmacokinetics of propofol in rats, children and adults,
Br J Clin Pharmacol, vol. 59, no. 6, pp. 705-11. DOI
Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltration,
Am J Kidney Dis, vol. 45, no. 2, pp. 360-71. DOI
- 2004
Mechanism-based pharmacokinetic-pharmacodynamic modeling of 5-HT1A receptor agonists: estimation of in vivo affinity and intrinsic efficacy on body temperature in rats,
J Pharmacol Exp Ther, vol. 308, no. 3, pp. 1012-20. DOI
Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients,
Br J Clin Pharmacol, vol. 57, no. 2, pp. 135-45. DOI
- 2002
Pharmacokinetics and effects of propofol 6% for short-term sedation in paediatric patients following cardiac surgery,
Br J Clin Pharmacol, vol. 54, no. 4, pp. 415-22. DOI
Pharmacokinetic-pharmacodynamic modelling of the hypothermic and corticosterone effects of the 5-HT1A receptor agonist flesinoxan,
Eur J Pharmacol, vol. 445, no. 1-2, pp. 43-54. DOI
A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia,
J Pharmacol Exp Ther, vol. 300, no. 1, pp. 330-8.
Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%,
Clin Pharmacol Ther, vol. 72, no. 6, pp. 670-84. DOI
Pharmacokinetic-pharmacodynamic modeling of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in rats,
J Pharmacol Exp Ther, vol. 303, no. 3, pp. 1130-7. DOI
- 2001
A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia,
Am J Physiol Regul Integr Comp Physiol, vol. 281, no. 6, pp. R2059-71.
- 2000
Enantioselective high-performance liquid chromatographic analysis of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin. Application to a pharmacokinetic-pharmacodynamic study in rats,
J Chromatogr B Biomed Sci Appl, vol. 738, no. 1, pp. 67-73.
- 1998
Metabolic and cardiovascular effects of the adenosine A1 receptor agonist N6-(p-sulfophenyl)adenosine in diabetic Zucker rats: influence of the disease on the selectivity of action,
J Pharmacol Exp Ther, vol. 287, no. 1, pp. 21-30.


