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2002
Li, G.L., van der Geest, R., Chanet, L., van Zanten, E., Danhof, M., Bouwstra, J.A. , In vitro iontophoresis of R-apomorphine across human stratum corneum. Structure-transport relationship of penetration enhancement, J Control Release, vol. 84, no. 1-2, pp. 49-57. DOI
1999
van Laar, T., Van der Geest, R., Danhof, M. , Future delivery systems for apomorphine in patients with Parkinson's disease, Adv Neurol, vol. 80, pp. 535-44.
1998
Bodde, H.E., Van Laar, T., Van der Geest, R., Danhof, M. , An integrated pharmacokinetic-pharmacodynamic approach to optimization of R-apomorphine delivery in Parkinson's disease, Adv Drug Deliv Rev, vol. 33, no. 3, pp. 253-263. DOI
van der Geest, R., van Laar, T., Kruger, P.P., Gubbens-Stibbe, J.M., Bodde, H.E., Roos, R.A., Danhof, M. , Pharmacokinetics, enantiomer interconversion, and metabolism of R-apomorphine in patients with idiopathic Parkinson's disease, Clin Neuropharmacol, vol. 21, no. 3, pp. 159-68.
van Laar, T., van der Geest, R., Danhof, M., Bodde, H.E., Goossens, P.H., Roos, R.A. , Stepwise intravenous infusion of apomorphine to determine the therapeutic window in patients with Parkinson's disease, Clin Neuropharmacol, vol. 21, no. 3, pp. 152-8.
van der Geest, R., Danhof, M., Bodde, H.E. , Validation and testing of a new iontophoretic continuous flow through transport cell, J Control Release, vol. 51, no. 1, pp. 85-91. DOI
1997
van der Geest, R., Kruger, P., Gubbens-Stibbe, J.M., van Laar, T., Bodde, H.E., Danhof, M. , Assay of R-apomorphine, S-apomorphine, apocodeine, isoapocodeine and their glucuronide and sulfate conjugates in plasma and urine of patients with Parkinson's disease, J Chromatogr B Biomed Sci Appl, vol. 702, no. 1-2, pp. 131-41.
van der Geest, R., Danhof, M., Bodde, H.E. , Iontophoretic delivery of apomorphine. I: In vitro optimization and validation, Pharm Res, vol. 14, no. 12, pp. 1798-803.
van der Geest, R., van Laar, T., Gubbens-Stibbe, J.M., Bodde, H.E., Danhof, M. , Iontophoretic delivery of apomorphine. II: An in vivo study in patients with Parkinson's disease, Pharm Res, vol. 14, no. 12, pp. 1804-10.