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2008
Geldof, M., Freijer, J. I, Peletier, L.A., van Beijsterveldt, L., Danhof, M. , Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex, Eur J Pharm Sci, vol. 33, no. 3, pp. 217-29. DOI
2007
Zuideveld, K.P., Van der Graaf, P.H., Peletier, L.A., Danhof, M. , Allometric scaling of pharmacodynamic responses: application to 5-Ht1A receptor mediated responses from rat to man, Pharm Res, vol. 24, no. 11, pp. 2031-9. DOI
2004
Zuideveld, K.P., Van der Graaf, P.H., Newgreen, D., Thurlow, R., Petty, N., Jordan, P., Peletier, L.A., Danhof, M. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of 5-HT1A receptor agonists: estimation of in vivo affinity and intrinsic efficacy on body temperature in rats, J Pharmacol Exp Ther, vol. 308, no. 3, pp. 1012-20. DOI
2003
Visser, S.A., Huntjens, D.R., van der Graaf, P.H., Peletier, L.A., Danhof, M. , Mechanism-based modeling of the pharmacodynamic interaction of alphaxalone and midazolam in rats, J Pharmacol Exp Ther, vol. 307, no. 2, pp. 765-75. DOI
Visser, S.A., Wolters, F.L., van der Graaf, P.H., Peletier, L.A., Danhof, M. , Dose-dependent EEG effects of zolpidem provide evidence for GABA(A) receptor subtype selectivity in vivo, J Pharmacol Exp Ther, vol. 304, no. 3, pp. 1251-7. DOI
Visser, S.A., Wolters, F.L., Gubbens-Stibbe, J.M., Tukker, E., Van Der Graaf, P.H., Peletier, L.A., Danhof, M. , Mechanism-based pharmacokinetic/pharmacodynamic modeling of the electroencephalogram effects of GABAA receptor modulators: in vitro-in vivo correlations, J Pharmacol Exp Ther, vol. 304, no. 1, pp. 88-101. DOI
2002
Visser, S.A., Smulders, C.J., Reijers, B.P., Van der Graaf, P.H., Peletier, L.A., Danhof, M. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of concentration-dependent hysteresis and biphasic electroencephalogram effects of alphaxalone in rats, J Pharmacol Exp Ther, vol. 302, no. 3, pp. 1158-67.
Visser, S.A., Gladdines, W.W., van der Graaf, P.H., Peletier, L.A., Danhof, M. , Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo, J Pharmacol Exp Ther, vol. 303, no. 2, pp. 616-26. DOI
Zuideveld, K.P., van Gestel, A., Peletier, L.A., Van der Graaf, P.H., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of the hypothermic and corticosterone effects of the 5-HT1A receptor agonist flesinoxan, Eur J Pharmacol, vol. 445, no. 1-2, pp. 43-54. DOI
Zuideveld, K.P., Treijtel, N., Maas, H.J., Gubbens-Stibbe, J.M., Peletier, L.A., van Der Graaf, P.H., Danhof, M. , A competitive interaction model predicts the effect of WAY-100,635 on the time course of R-(+)-8-hydroxy-2-(di-n-propylamino)tetralin-induced hypothermia, J Pharmacol Exp Ther, vol. 300, no. 1, pp. 330-8.
Zuideveld, K.P., Rusic-Pavletic, J., Maas, H.J., Peletier, L.A., Van der Graaf, P.H., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in rats, J Pharmacol Exp Ther, vol. 303, no. 3, pp. 1130-7. DOI
2001
Zuideveld, K.P., Maas, H.J., Treijtel, N., Hulshof, J., van der Graaf, P.H., Peletier, L.A., Danhof, M. , A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia, Am J Physiol Regul Integr Comp Physiol, vol. 281, no. 6, pp. R2059-71.