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2009
Huntjens, D.R., Spalding, D.J., Danhof, M., Della Pasqua, O.E. , Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors, Eur J Pain, vol. 13, no. 5, pp. 448-57. DOI
Maas, H., Danhof, M., Della Pasqua, O. , Analysis of the relationship between age and treatment response in migraine, Cephalalgia. DOI
Ince, I, de Wildt, S.N., Tibboel, D., Danhof, M., Knibbe, C.A. , Tailor-made drug treatment for children: creation of an infrastructure for data-sharing and population PK-PD modeling, Drug Discov Today, vol. 14, no. 5-6, pp. 316-20. DOI
Verpoorte, R., Crommelin, D., Danhof, M., Gilissen, L.J., Schuitmaker, H., van der Greef, J., Witkamp, R.F. , Commentary: "A systems view on the future of medicine: inspiration from Chinese medicine?", J Ethnopharmacol, vol. 121, no. 3, pp. 479-81. DOI
Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., de Jong, H.W., Dijkstra, J., van der Weerd, L., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Changes in GABAA receptor properties in amygdala kindled animals: in vivo studies using [11C]flumazenil and positron emission tomography, Epilepsia, vol. 50, no. 1, pp. 88-98. DOI
Ploeger, B.A., Smeets, J., Strougo, A., Drenth, H.J., Ruigt, G., Houwing, N., Danhof, M. , Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex, Anesthesiology, vol. 110, no. 1, pp. 95-105. DOI
Press, R.R., Ploeger, B.A., den Hartigh, J., van der Straaten, T., van Pelt, J., Danhof, M., de Fijter, J.W., Guchelaar, H.J. , Explaining variability in tacrolimus pharmacokinetics to optimize early exposure in adult kidney transplant recipients, Ther Drug Monit, vol. 31, no. 2, pp. 187-97. DOI
Muller, A.E., Oostvogel, P.M., DeJongh, J., Mouton, J.W., Steegers, E.A., Dorr, P.J., Danhof, M., Voskuyl, R.A. , Pharmacokinetics of amoxicillin in maternal, umbilical cord, and neonatal sera, Antimicrob Agents Chemother, vol. 53, no. 4, pp. 1574-80. DOI
Ploeger, B.A., Graaf, P.H., Danhof, M. , Incorporating receptor theory in mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling, Drug Metab Pharmacokinet, vol. 24, no. 1, pp. 3-15. DOI
2008
Santen, G., Danhof, M., Della Pasqua, O. , Evaluation of treatment response in depression studies using a Bayesian parametric cure rate model, J Psychiatr Res, vol. 42, no. 14, pp. 1189-97. DOI
Santen, G., Gomeni, R., Danhof, M., Della Pasqua, O. , Sensitivity of the individual items of the Hamilton depression rating scale to response and its consequences for the assessment of efficacy, J Psychiatr Res, vol. 42, no. 12, pp. 1000-9. DOI
Ravenstijn, P.G., Merlini, M., Hameetman, M., Murray, T.K., Ward, M.A., Lewis, H., Ball, G., Mottart, C., de Ville Goyet, C., Lemarchand, T., van Belle, K., O'Neill, M.J., Danhof, M., de Lange, E.C. , The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments, J Pharmacol Toxicol Methods, vol. 57, no. 2, pp. 114-30. DOI
Geldof, M., Freijer, J. I, Peletier, L.A., van Beijsterveldt, L., Danhof, M. , Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex, Eur J Pharm Sci, vol. 33, no. 3, pp. 217-29. DOI
Peeters, M.Y., Bras, L.J., DeJongh, J., Wesselink, R.M., Aarts, L.P., Danhof, M., Knibbe, C.A. , Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients, Clin Pharmacol Ther, vol. 83, no. 3, pp. 443-51. DOI
van Steeg, T.J., Freijer, J., Danhof, M., de Lange, E.C. , Mechanism-based pharmacodynamic modeling of S(-)-atenolol: estimation of in vivo affinity for the beta1-adrenoceptor with an agonist-antagonist interaction model, J Pharmacol Exp Ther, vol. 324, no. 3, pp. 1234-42. DOI
Huntjens, D.R., Strougo, A., Chain, A., Metcalf, A., Summerfield, S., Spalding, D.J., Danhof, M., Della Pasqua, O. , Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats, Br J Pharmacol, vol. 153, no. 5, pp. 1072-84. DOI
Peeters, M.Y., Aarts, L.P., Boom, F.A., Bras, L.J., Tibboel, D., Danhof, M., Knibbe, C.A. , Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients, Eur J Clin Pharmacol, vol. 64, no. 3, pp. 329-34. DOI
Groenendaal, D., Freijer, J., Rosier, A., de Mik, D., Nicholls, G., Hersey, A., Ayrton, A.D., Danhof, M., de Lange, E.C. , Pharmacokinetic/pharmacodynamic modelling of the EEG effects of opioids: the role of complex biophase distribution kinetics, Eur J Pharm Sci, vol. 34, no. 2-3, pp. 149-63. DOI
Geldof, M., Freijer, J. I, van Beijsterveldt, L., Langlois, X., Danhof, M. , Pharmacokinetic-pharmacodynamic modelling of fluvoxamine 5-HT transporter occupancy in rat frontal cortex, Br J Pharmacol, vol. 154, no. 6, pp. 1369-78. DOI
Muller, A.E., DeJongh, J., Oostvogel, P.M., Voskuyl, R.A., Dorr, P.J., Danhof, M., Mouton, J.W. , Amoxicillin pharmacokinetics in pregnant women with preterm premature rupture of the membranes, Am J Obstet Gynecol, vol. 198, no. 1, pp. 108 e1-6. DOI
Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the effectiveness and safety of buprenorphine and fentanyl in rats, Pharm Res, vol. 25, no. 1, pp. 183-93. DOI
van Steeg, T.J., Boralli, V.B., Krekels, E.H., Slijkerman, P., Freijer, J., Danhof, M., de Lange, E.C. , Influence of plasma protein binding on pharmacodynamics: Estimation of in vivo receptor affinities of beta blockers using a new mechanism-based PK-PD modelling approach, J Pharm Sci. DOI
Clinckers, R., Smolders, I, Michotte, Y., Ebinger, G., Danhof, M., Voskuyl, R.A., Della Pasqua, O. , Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain, Br J Pharmacol, vol. 155, no. 7, pp. 1127-38. DOI
Muller, A.E., Dorr, P.J., Mouton, J.W., De Jongh, J., Oostvogel, P.M., Steegers, E.A., Voskuyl, R.A., Danhof, M. , The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women, Br J Clin Pharmacol, vol. 66, no. 6, pp. 866-74. DOI
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