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2000
Cleton, A., Odman, J., Van der Graaf, P.H., Ghijsen, W., Voskuyl, R., Danhof, M. , Mechanism-based modeling of functional adaptation upon chronic treatment with midazolam, Pharm Res, vol. 17, no. 3, pp. 321-7.
Cleton, A., Altorf, B.A., Voskuyl, R.A., Danhof, M. , Effect of amygdala kindling on the central nervous system effects of tiagabine: EEG effects versus brain GABA levels, Br J Pharmacol, vol. 130, no. 5, pp. 1037-44. DOI
1999
Cleton, A., Van der Graaf, P.H., Ghijsen, W., Voskuyl, R., Danhof, M. , Mechanism-based modeling of adaptive changes in the pharmacodynamics of midazolam in the kindling model of epilepsy, Pharm Res, vol. 16, no. 11, pp. 1702-9.
Cleton, A., Mazee, D., Voskuyl, R.A., Danhof, M. , Rate of change of blood concentrations is a major determinant of the pharmacodynamics of midazolam in rats, Br J Pharmacol, vol. 127, no. 1, pp. 227-35. DOI
Cleton, A., de Greef, H.J., Edelbroek, P.M., Voskuyl, R.A., Danhof, M. , Application of a combined "effect compartment/indirect response model" to the central nervous system effects of tiagabine in the rat, J Pharmacokinet Biopharm, vol. 27, no. 3, pp. 301-23.
Cleton, A., de Greef, H.J., Edelbroek, P.M., Voskuyl, R.A., Danhof, M. , Stereoselective central nervous system effects of the R- and S-isomers of the GABA uptake blocker N-(4, 4-di-(3-methylthien-2-yl)but-3-enyl) nipecotic acid in the rat, Br J Pharmacol, vol. 128, no. 8, pp. 1651-8. DOI
1998
1995
Mathot, R.A., Cleton, A., Soudijn, W., AP, I.J., Danhof, M. , Pharmacokinetic modelling of the haemodynamic effects of the A2a adenosine receptor agonist CGS 21680C in conscious normotensive rats, Br J Pharmacol, vol. 114, no. 4, pp. 761-8.
1994
Irth, H., Cleton, A., Mathot, R.A., Danhof, M., AP, I.J., Tjaden, U.R., van der Greef, J. , Liquid chromatographic determination of the adenosine receptor agonist CGS 21680 in blood using on-line solid-phase extraction on a phenylboronic acid support and fluorescence detection, J Chromatogr B Biomed Appl, vol. 658, no. 1, pp. 207-12.