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2007
Freijer, J. I, Post, T.M., Ploeger, B.A., DeJongh, J., Danhof, M. , Application of the convection-dispersion equation to modelling oral drug absorption, Bull Math Biol, vol. 69, no. 1, pp. 181-95. DOI
Yassen, A., Olofsen, E., Romberg, R., Sarton, E., Teppema, L., Danhof, M., Dahan, A. , Mechanism-based PK/PD modeling of the respiratory depressant effect of buprenorphine and fentanyl in healthy volunteers, Clin Pharmacol Ther, vol. 81, no. 1, pp. 50-8. DOI
Geldof, M., Freijer, J., van Beijsterveldt, L., Timmerman, P., Ahnaou, A., Drinkenburg, W.H., Danhof, M. , Population pharmacokinetic model of fluvoxamine in rats: utility for application in animal behavioral studies, Eur J Pharm Sci, vol. 30, no. 1, pp. 45-55. DOI
Yassen, A., Olofsen, E., Kan, J., Dahan, A., Danhof, M. , Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine, Clin Pharmacokinet, vol. 46, no. 5, pp. 433-47. DOI
Danhof, M., de Jongh, J., De Lange, E.C., Della Pasqua, O., Ploeger, B.A., Voskuyl, R.A. , Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis, Annu Rev Pharmacol Toxicol, vol. 47, pp. 357-400. DOI
Yassen, A., Olofsen, E., van Dorp, E., Sarton, E., Teppema, L., Danhof, M., Dahan, A. , Mechanism-based pharmacokinetic-pharmacodynamic modelling of the reversal of buprenorphine-induced respiratory depression by naloxone : a study in healthy volunteers, Clin Pharmacokinet, vol. 46, no. 11, pp. 965-80. DOI
2006
Yassen, A., Kan, J., Olofsen, E., Suidgeest, E., Dahan, A., Danhof, M. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of the respiratory-depressant effect of buprenorphine and fentanyl in rats, J Pharmacol Exp Ther, vol. 319, no. 2, pp. 682-92. DOI
Dahan, A., Yassen, A., Romberg, R., Sarton, E., Teppema, L., Olofsen, E., Danhof, M. , Buprenorphine induces ceiling in respiratory depression but not in analgesia, Br J Anaesth, vol. 96, no. 5, pp. 627-32. DOI
Peeters, M.Y., Prins, S.A., Knibbe, C.A., DeJongh, J., van Schaik, R.H., van Dijk, M., van der Heiden, I.P., Tibboel, D., Danhof, M. , Propofol pharmacokinetics and pharmacodynamics for depth of sedation in nonventilated infants after major craniofacial surgery, Anesthesiology, vol. 104, no. 3, pp. 466-74. DOI
Yassen, A., Olofsen, E., Romberg, R., Sarton, E., Danhof, M., Dahan, A. , Mechanism-based pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine in healthy volunteers, Anesthesiology, vol. 104, no. 6, pp. 1232-42. DOI
van Dorp, E., Yassen, A., Sarton, E., Romberg, R., Olofsen, E., Teppema, L., Danhof, M., Dahan, A. , Naloxone reversal of buprenorphine-induced respiratory depression, Anesthesiology, vol. 105, no. 1, pp. 51-7. DOI
Nugroho, A.K., Romeijn, S.G., Zwier, R., de Vries, J.B., Dijkstra, D., Wikstrom, H., Della-Pasqua, O., Danhof, M., Bouwstra, J.A. , Pharmacokinetics and pharmacodynamics analysis of transdermal iontophoresis of 5-OH-DPAT in rats: in vitro-in vivo correlation, J Pharm Sci, vol. 95, no. 7, pp. 1570-85. DOI
Peeters, M.Y., Prins, S.A., Knibbe, C.A., Dejongh, J., Mathot, R.A., Warris, C., van Schaik, R.H., Tibboel, D., Danhof, M. , Pharmacokinetics and pharmacodynamics of midazolam and metabolites in nonventilated infants after craniofacial surgery, Anesthesiology, vol. 105, no. 6, pp. 1135-46. DOI
2005
Liefaard, L.C., Ploeger, B.A., Molthoff, C.F., Boellaard, R., Lammertsma, A.A., Danhof, M., Voskuyl, R.A. , Population pharmacokinetic analysis for simultaneous determination of B (max) and K (D) in vivo by positron emission tomography, Mol Imaging Biol, vol. 7, no. 6, pp. 411-21. DOI
Schaddelee, M.P., Collins, S.D., DeJongh, J., de Boer, A.G., Ijzerman, A.P., Danhof, M. , Pharmacokinetic/pharmacodynamic modelling of the anti-hyperalgesic and anti-nociceptive effect of adenosine A1 receptor partial agonists in neuropathic pain, Eur J Pharmacol, vol. 514, no. 2-3, pp. 131-40. DOI
Prins, S.A., Peeters, M.Y., Houmes, R.J., van Dijk, M., Knibbe, C.A., Danhof, M., Tibboel, D. , Propofol 6% as sedative in children under 2 years of age following major craniofacial surgery, Br J Anaesth, vol. 94, no. 5, pp. 630-5. DOI
Nugroho, A.K., Li, L., Dijkstra, D., Wikstrom, H., Danhof, M., Bouwstra, J.A. , Transdermal iontophoresis of the dopamine agonist 5-OH-DPAT in human skin in vitro, J Control Release, vol. 103, no. 2, pp. 393-403. DOI
Nugroho, A.K., Della-Pasqua, O., Danhof, M., Bouwstra, J.A. , Compartmental modeling of transdermal iontophoretic transport II: in vivo model derivation and application, Pharm Res, vol. 22, no. 3, pp. 335-46.
Knibbe, C.A., Zuideveld, K.P., Aarts, L.P., Kuks, P.F., Danhof, M. , Allometric relationships between the pharmacokinetics of propofol in rats, children and adults, Br J Clin Pharmacol, vol. 59, no. 6, pp. 705-11. DOI
Dahan, A., Yassen, A., Bijl, H., Romberg, R., Sarton, E., Teppema, L., Olofsen, E., Danhof, M. , Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats, Br J Anaesth, vol. 94, no. 6, pp. 825-34. DOI
Yassen, A., Olofsen, E., Dahan, A., Danhof, M. , Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine and fentanyl in rats: role of receptor equilibration kinetics, J Pharmacol Exp Ther, vol. 313, no. 3, pp. 1136-49. DOI
Visser, C.C., Stevanovic, S., Voorwinden, L.H., van Bloois, L., Gaillard, P.J., Danhof, M., Crommelin, D.J., de Boer, A.G. , Targeting liposomes with protein drugs to the blood-brain barrier in vitro, Eur J Pharm Sci, vol. 25, no. 2-3, pp. 299-305. DOI
Li, G.L., de Vries, J.J., van Steeg, T.J., van den Bussche, H., Maas, H.J., Reeuwijk, H.J., Danhof, M., Bouwstra, J.A., van Laar, T. , Transdermal iontophoretic delivery of apomorphine in patients improved by surfactant formulation pretreatment, J Control Release, vol. 101, no. 1-3, pp. 199-208. DOI
Schaddelee, M.P., Read, K.D., Cleypool, C.G., Ijzerman, A.P., Danhof, M., de Boer, A.G. , Brain penetration of synthetic adenosine A1 receptor agonists in situ: role of the rENT1 nucleoside transporter and binding to blood constituents, Eur J Pharm Sci, vol. 24, no. 1, pp. 59-66. DOI
Li, G.L., Van Steeg, T.J., Putter, H., Van Der Spek, J., Pavel, S., Danhof, M., Bouwstra, J.A. , Cutaneous side-effects of transdermal iontophoresis with and without surfactant pretreatment: a single-blinded, randomized controlled trial, Br J Dermatol, vol. 153, no. 2, pp. 404-12. DOI
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